What is the difference between cow’s milk allergy and lactose intolerance?

Cow’s milk allergy is often confused with lactose intolerance. Hypersensitivity to food can be non-allergic hypersensitivity and allergic hypersensitivity. In the non-allergic type, also called intolerance, the immune system is not involved. Lactose intolerance is an example of this type of hypersensitivity, which is due to lack of the lactose-degrading enzyme lactase. The allergic hypersensitivity, also called food allergy, can be divided into Immunoglobulin E-mediated and non-IgE-mediated food allergy. Cow’s milk allergy can be IgE-mediated or non-IgE-mediated, whereby it has been shown that IgE-mediated reactions are more common in infancy and non-IgE-mediated reactions dominate in adults.